After adjustments were made for age, sex, operation levels, history of stroke and CHD, anesthesia time, drinking status, intraoperative hypotension, CRP, Hb, fluid and blood transfusion volume, urinary volume, bleeding volume, and ASA Physical Status Classification System, participants with CHS score ≥ 10 had 57% decreased ORs of AKI (OR = 0.43, 95% CI = 0.23, 0.79), compared with participants with CHS score ≤ 7 (Table 2). This evidence concerns the gene CRP and Stroke.