However, in contrast to the seminal description of IA in CGD mice by Morgenstern et al (Morgenstern et al., 1997) where IL-1β lung mRNA on Northern blot analysis started to decrease one week after A. fumigatus infection, we found no evidence of resolution in pulmonary IL-1β at 7 or 17 days following A. fumigatus and A. nidulans infection. Here, IL1B is linked to chronic granulomatous disease.