Thbs1 has been implicated in the regulation of latent Tgfβ activation and macrophage‐derived Thbs1 has been proven to promote the development of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NAFLD/NASH).55, 56. The gene discussed is TGFB1; the disease is metabolic dysfunction-associated steatohepatitis.