We analyzed the correlation between ACOX1 and the EMT-related genes and found a positive correlation with cadherin 1 (CDH1), CDH2, cyclin-dependent kinase-like 2 (CDK2), and epithelial cell adhesion molecule, and a negative correlation with matrix metalloproteinase MMP9 and vimentin, suggesting that ACOX1 might be regulated by EMT and affect its metastasis in ccRCC. Here, CDKL2 is linked to nonpapillary renal cell carcinoma.