AGT and fetal growth restriction: The only plausible explanation for a decline in renal plasma flow in our study, where dexamethasone caused IUGR, is an increase in preglomerular resistance due to other factors, such as an increase in renal levels of angiotensin II49, 50 and increased expression of angiotensinogen and angiotensin II type 1 receptor (AT1R),51 decrease in renal nitric oxide production,51 reduction of vascular compliance,52 which is associated with low birth weight53 or altered sympathetic activity.54