SLC6A6 and cardiac hypertrophy: It has also been shown that STZ‐treated C57BL/6 mice following TauT gene knockout displayed more advanced diabetic nephropathy than STZ‐induced C57BL/6 mice, as evidenced by considerable GBM thickening, enlarged mesangial matrix, fibrous thickening of efferent and afferent arterioles with severe dilatation and arteriosclerosis, and major renal hypertrophy.