Primarily, we assessed the expression levels of ZBTB48 in CGGA and TCGA-glioma databases, and the obtained data indicated that the expression level of ZBTB48 elevated accompanied with the ascending grade of glioma, and its high expression was also observed in IDH1 wild-type and 1p19q non-codeletion groups (Fig. S8a-h). Here, IDH1 is linked to central nervous system cancer.