Compared with those observed in the non-ASC patients, the expression levels of ARG1, collagen 1A1, vimentin, fibronectin, and Ki67 in the patients with ASC were markedly increased (Fig. 6), which was consistent with our observations in murine models, indicating the involvement of ARG1 in ASC patients. The gene discussed is MKI67; the disease is Tako-tsubo cardiomyopathy.