HLA-B and central nervous system cancer: HLA-I supertypes were largely represented among the PDX models (Fig. 5, Supplementary Fig. S5 and Supplementary Table S3): all 5 HLA-A supertypes in sarcoma, neuroblastoma, high-grade glioma PDXs, and 5–7 HLA-B supertypes in sarcoma and neuroblastoma.