When considering PDX models with available RNA-Seq in comparison to normal WES, all alleles from the three classical HLA class I loci were detected in Ewing sarcoma, non-rhabdomyosarcoma soft tissue sarcoma and nephroblastoma PDXs, and all except single HLA-B and -C alleles were detected in alveolar rhabdomyosarcoma and high-grade glioma PDXs. Here, HLA-B is linked to Nephroblastoma.