TFRC and infection: To gain insight as to how TFR impact Fo B behavior to potentially alter susceptibility to infection, we performed RNA-seq on splenic Fo B isolated from Bcl6fl/fl and FoxP3CreBcl6fl/fl mice at two weeks post challenge, when Brucella burdens are similar in these strains (S9A Fig), and on Fo B from naïve animals (S10 Fig and S1 Table).