CLEC12A and cancer: The retentionof antigen in early endosomes has been shown slightly longer upontargeting Clec12a, thus promoting XP.142 Clec12a-mediated delivery of keyhole limpet hemocyanin (KLH) tomoDCs, pDCs, DC2s, or DC1s led to enhanced XP, IFN-γ production,and CD4+ T cell proliferation compared to untargeted controls.142 These findings indicate a potential use forClec12a as a target in cancer vaccines.