ABCB6 and neoplasm: However, several studies have demonstratedthat ABC transportersplay an additional fundamental role in tumor biology; there is strongevidence that these proteins might be involved in the transport oftumor-augmenting molecules and/or protein–protein interactionsthat affect cancer aggressiveness, progression, and the patient prognosis.Apart from these findings, the relationship between cancer-causinginflammation and ABC proteins is almost intuitive due to their effluxfunction, since inflammation is regulated by multiple molecules, someof which are substrates of these molecular pumps.