Compared to BD, the major expanded CD4+ T cell clusters in VKHD were C3 – T (MIX), C6 – Tem (MIX) and C7 – Tem (GZMH+), whereas naïve (C0), Tcm (C1) and Treg (C2) showed little or minor changes (Figure 3c). Here, CD4 is linked to Behcet disease.