RNPC3 and amyotrophic lateral sclerosis: Moreover, ALS-linked mutations of RBPs, have been shown to perturb post-transcriptional RNA processing, mRNA trafficking and local translation, stress granule formation/dissolution kinetics, and/or mRNA stability in addition to altering RNP condensate behavior in vivo and in cellular disease models (Kim et al., 2013; Coyne et al., 2015; Murakami et al., 2015; Gopal et al., 2017; Fratta et al., 2018; Wolozin and Ivanov, 2019; Hallegger et al., 2021).