In addition, examples of aberrant condensates associated with pathologic post-translational modifications of wild type RBPs or other disordered proteins such as tau, suggest that aberrant phase separation may also be relevant in the setting of sporadic neurodegenerative disease (Cohen et al., 2015; Wegmann et al., 2018; Yu et al., 2021; Lu et al., 2022). The gene discussed is MAPT; the disease is neurodegenerative disease.