TARDBP and amyotrophic lateral sclerosis: Inherited and rare sporadic cases of ALS/FTD have been linked to mutations in ~40 genes, many of which encode RBPs, including transactive DNA response binding protein of 43 kDa (TDP-43) and fused in sarcoma (FUS) (Sreedharan et al., 2008; Kwiatkowski et al., 2009; Vance et al., 2009; Kim G. et al., 2020).