NUP62 and amyotrophic lateral sclerosis: Abnormal Nup62 labeling of the nuclear envelope and mislocalization of Importin β-1 has been observed in spinal motor neurons of SOD1-G93A transgenic mice, and Nup62 abnormalities were found in spinal motor neurons of SOD1-ALS cases (Kinoshita et al., 2009; Nagara et al., 2013).