Similarly, Nup52 has been shown to colocalize with cytoplasmic TDP-43 aggregates in spinal motor neurons of sALS cases and Nup98 has been shown to colocalize with cytoplasmic TDP-43 aggregates in neurons of the dentate gyrus of C9orf72 ALS/FTD cases (Gleixner et al., 2022). The gene discussed is TARDBP; the disease is frontotemporal dementia.