The results showed that, compared to the control group, the obese PCOS group had more severe disorders of lipid metabolism (TG, TC, LDL-C, HDL-C), insulin resistance (FIns, HOMA-IR), and sex hormone disorders (TT, FAI, SHBG), further confirming that there is a correlation between PCOS and endocrine and metabolic disorders. The gene discussed is SHBG; the disease is Other metabolic disease.