CSF1 and Infertility: Lastly, if CSF1 reduction is confirmed as one of the culprits in the adverse effects of EDCs, it could be used as target for the development of novel therapeutic agents to treat cases of deficient spermatogenesis or infertility, by researching pharmacological ways to palliate or prevent CSF1 decrease in testis and restore or support tMΦ-SSCs interactions.