The role of Bcl-2 as a biomarker in rhabdomyosarcoma has been the subject of several review articles [16, 93, 94] and there are recent papers trying to correlate levels of Bcl-2 and sensitivity to Nab-paclitaxel [86] in rhabdomyosarcoma and ES. The gene discussed is BCL2; the disease is rhabdomyosarcoma.