We found that the frequency of selected cells is significantly higher in the CLR group compared to DII and background at k = 40 (p = 8.1e−8 and p = 0.019, Wilcoxon test, respectively) (Figures 3G and S13) and composed of mostly tumor cells (15%), CD163+ macrophages (15%), and B cells (8%) (Figures 3H, S17, S18, and S19). Here, CD163 is linked to neoplasm.