Measurements of the selected proteins in all the participants of the study revealed that in the active stage of GPA, levels of IGFBP-2 were the highest (active: 210 ± 30, remission: 140 ± 15 and HC: 85 ± 8 ng/mL, p<0.05) (Figure 2A). Here, IGFBP2 is linked to granulomatosis with polyangiitis.