To address the implications of the covalent link between the APC-binding molecule CCL19 and the cancer neoepitopes in CCL19_Neo5, we designed a tumor experiment comparing the efficacy of immunizing with the fusion construct CCL19_Neo5 or with the combination of NT_Neo5 and a pDNA encoding CCL19 (pCCL19) (Figure 3A). The gene discussed is CCL19; the disease is neoplasm.