Cox analysis confirmed that MPO level was an independent risk factor for post-catheter ablation AF recurrence after adjustment for age, sex, BMI, smoking, hypertension, diabetes, dyslipidemia, stroke, coronary artery disease, eGFR, LAD, LVEF, LAV, and duration of AF, regardless of MPO as a continuous variable, a categorical variable or an ordinal variable (Table 3). The gene discussed is MPO; the disease is atrial fibrillation.