GHR and cancer: Notably, several pathways involved in cancer and hematopoietic malignancies development were identified by Reactome analysis of the top ten genes analyzed in this study, including Interferon alpha/beta signaling (73–75), caspases and Rho GTPase activity (76), GHR signaling pathway (77–79), Integrin signaling (80), non-receptor Tyrosine Kinases activity (81), and FGF/FGFR pathways (82).