The highest median [177Lu]Lu-NeoB binding (0.051% AA/mm2, 95% confidence interval (CI) = 0.034 – 0.183%) was observed in primary PCa samples, while median [177Lu]Lu-PSMA-617 binding (10.74% AA/mm2, 95% CI = 5.52 – 13.19%) was highest in CRPC samples. This evidence concerns the gene FOLH1 and posterior cortical atrophy.