TRPM7 and brain ischemia: Therefore, the specific objectives of the present work were as follows: (1) to evaluate miR135a expression in temporoparietal cortex of ischemic rats; (2) to investigate the effect of the icv infusion of miR135a on ischemic damage and neurological functions; and (3) to verify whether miR135a effects on brain ischemia development may be mediated by an alteration of TRPM7 expression.