Moreover, while no differences in the overall relative abundance of CD8+ cells were observed between the two genotypes, the CD8+ T cells of the WT tumours displayed a markedly higher relative proportion of PD‐1‐positive cells than those of the TAZ‐KO tumours (Fig. 5C), consistent with the conclusion that TAZ in the cancer cells promotes CD8+ T cell exhaustion in the immune TME. This evidence concerns the gene WWTR1 and neoplasm.