Further functional annotation (Figure 3D) revealed that these myocardial disorder factors enriched cardiac pathogenesis pathways (e.g., JAK-STAT signaling pathway, Ras protein signal transduction, regulation of small GTPase mediated signal transduction, and positive regulation of GTPase activity) and relevant functional modules (e.g., apoptosis, platelet activation, cell–cell adhesion, vascular disease, cells, and molecules involved in local acute inflammatory response). The gene discussed is SOAT1; the disease is myocardial disorder.