The nine enriched KEGG pathways include Pathways in cancer (hsa05200) [95], Estrogen signaling pathway (hsa04915) [95], Rap1 signaling pathway (hsa04015) [96], Neurotrophin signaling pathway (hsa04722) [97], and Fluid shear stress and atherosclerosis (hsa05418) [98] have been previously reported in ER+ BC. Here, BDNF is linked to breast cancer.