These external tools include predictors for bioactivity available from the Ersilia Model Hub; namely, a version of the malaria inhibition prediction (MAIP)23 model for P. falciparum and ChemTB24 for M. tuberculosis, as well as ADME@NCATS25,26 suite for ADME predictions for solubility, microsomal stability in rat and human, and CYP inhibition (CYP2C9, CYP2D6, CYP3A4). The gene discussed is CYP2C9; the disease is malaria.