NOTCH3 and neoplasm: Of the genes, “rhythmic in tumor only” were 95 genes classified as “multicellular organism development” or “cell differentiation.” These included genes associated with carcinogenesis such as Aurkb, Wnk2, Wnt11, Wnt7b, Notch3, Sim 1, and Sim2 (Figs. 5E and S2) (31, 32, 33, 34, 35, 36, 37).