Of these, 6 genes (nudix hydrolase 1, phosphatase, orphan 1, ND4L, Serine palmitoyltransferase small subunit A, PLPP1, SLCO1A2) had HR > 1 indicating an increased risk of disease progression or death in TGCT patients; while 9 genes (PLGRKT, IDH2, histone deacetylase 3 [HDAC3], MTMR8, deoxythymidylate kinase, NT5C3A, SLC25A14, mediator complex subunit 10, NDUFA10) had HR < 1 indicating a decreased risk of disease progression or death in TGCT patients. This evidence concerns the gene HDAC3 and testicular germ cell tumor.