As shown by Figure 2A, the TCGA project found a correlation between highly expressed SPON2 and a poor OS prognosis for the cancer types BLCA (P = .011), KIRC (P = .0096), LGG (P = .00011), LIHC (P = .027), LUSC (P = .031), and mesothelioma (P = .012). This evidence concerns the gene SPON2 and cancer.