Recent research has reported AQP3 expression in UEC; however, no report has compared its expression across histological subtypes of other carcinomas, such as ovarian cancer.[28] Some studies have also described a relationship between VIM and AQP3 expression and hypoxia.[29,30] We found that AQP3 overexpression is a potential biomarker for the differential diagnosis of ECs. Here, AQP3 is linked to carcinoma.