Since the previous studies have explored the role of the signature genes METTL7B, SSTR2, OXTR, CDKN2C, and H19 in glioma, while TNFRSF11B has been poorly studied, we examined the functional impact of TNFRSF11B on LGG cell behavior [39–44]. The gene discussed is SSTR2; the disease is glioma.