An alternative anti-VEGF antibody, Ranibizumab, a human monoclonal antibody fragment derived from the parent antibody Bevacizumab [47] has been licenced and approved for treatment of retinal vasoproliferative disorders in adults and also for ROP by the National Health Service (NHS England) [62] and European Medicines Agency (EMA) [63] following completion of the RAINBOW trial [64]—225 participants, randomized to ranibizumab 0.2 mg, ranibizumab 0.1 mg, and laser photocoagulation therapy. Here, VEGFA is linked to retinopathy of prematurity.