To determine whether fatty acid metabolism is altered in ovarian cancer tissue, we first evaluated the gene expression of fatty acid synthases (ACC1, FASN), fatty acid desaturases (SCD1, FADS1, FADS2) and fatty acid elongase 1–6 (ELOVL1–6) in ovarian tumor tissues and normal ovarian tissues. This evidence concerns the gene FADS2 and ovarian neoplasm.