Past medical history revealed HIV infection since 2010 (controlled with bictegravir/emtricitabine/tenofovir alafenamide since 2010 and with stable CD4+ T-cell counts since many years), hepatitis B virus (HBV) infection in 1994, cured Treponema pallidum infection and anal carcinoma in remission since 2019. Here, CD4 is linked to HIV infectious disease.