Moreover, we quantified RIME levels in ESCC cells that were subjected to various TAMs secreted cytokines, including interleukin (IL)‐6, tumour necrosis factor (TNF)‐α, transforming growth factor (TGF)‐β and vascular endothelial growth factor (VEGF)16, 17(Figure 1G and Figure S1F,G). Here, IL6 is linked to esophageal squamous cell carcinoma.