We also discovered 14 hub genes, including TYROBP, CD44, BGN, FCGR3A, CD53, CXCR4, FN1, SPP1, IGF1, CCND1, MMP9, IL2RG, IL6 and CTGF, which were crucial in the development of CC and obesity. The gene discussed is CXCR4; the disease is obesity due to melanocortin 4 receptor deficiency.