HNF4A and MODY: Heterozygous missense mutations in the HNF4A gene (NM_175914.5), I159T (c.476T>C, p.Ile159Thr), W179C (c.537G>C, p.Trp179Cys), and D260N (c.778G>A, p.Asp260Asn), were identified in the probands of three unrelated MODY families, which co-segregated with hyperglycemic phenotypes in their families (Figure 1).