CAMP and periodontitis: The increase in the number and activation of neutrophils in periodontitis results in an elevated level of LL-37, as neutrophile is the primary source of this peptide [11–13] since salivary LL-37 is derived from neutrophils that infiltrate the oral cavity via the junctional epithelium at sites of inflammation with further sources including both epithelial cells of the gingiva and the mucosa [14–16].