The ivw-RE analysis revealed that CKD may lead to higher levels of GROα (β = 0.144, 95% CI 0.010 - 0.278, P = 0.036), and reduced eGFR may lead to elevated levels of SCF (β = -1.998, 95% CI -2.773 - -1.223, P = 0.000). Here, KITLG is linked to chronic kidney disease.