Results: Age, cyclosporine use, and pre-LT GFR independently associated with new onset CKD; 10 proteins associated with new CKD in proteomic evaluations when GFR inputted as a continuous variable including: Cyc, alpha-1-microglobulin, beta-2-microglobulin, TFF3, FABP, factor VII, apolipoprotein H, apolipoprotein CIII, chromogranin A, and CD40 (notably NGAL was not associated with CKD). The gene discussed is CD40; the disease is chronic kidney disease.