Analysis of the expression of GAPDS mRNA in different cancer cell lines showed a high content of GAPDS mRNA in some lines of melanoma cells (ArrayExpress database, www.ebi.ac.uk/array-express, accession numbers E-MTAB-37, E-MTAB-62, E-GEOD- 10843 and E-GEOD-7127). This evidence concerns the gene GAPDHS and melanoma.