In addition to IDH genotyping, genetic phenotypes and molecular characteristics such as chromosome 1p/19q co-deletion, O-6-methylguanine-DNA methyltransferase (MGMT) methylation, and phosphatase and tensin homologue deleted on chromosome 10 (PTEN) genotyping also have important effects on the prognosis and treatment of gliomas (14). The gene discussed is MGMT; the disease is glioma.