The first 10 mutated genes in ccRCC patients with high KIFscores were VHL, PBRM1, TTN, SETD2, BAP1, MUC16, MTOR, HMCN1, XIRP2, and PTEN, and the first 10 mutated genes in ccRCC patients with low KIFscores were VHL, PBRM1, TTN, SETD2, MTOR, KDM5C, LRP2, MUC16, ANK3, and DNAH9. Here, KDM5C is linked to nonpapillary renal cell carcinoma.