In tumor cells, favorable DFS/RFS were also related to studies from univariate analysis and the gastrointestinal system (HR = 0.667, 95% CI = 0.482-0.923, <i>p</i> = 0.015 and HR = 0.566, 95% CI = 0.330-0.971, <i>p</i> = 0.039).<h4>Conclusions</h4>STING expression in tumor cells is associated with favorable outcome in solid tumors.<h4>Systematic review registration</h4>https://www.crd.york.ac.uk/prospero/, registration number: CRD42023427027. This evidence concerns the gene STING1 and neoplasm.