It is worth pointing out that genetic diagnosis of FH can be expanded with genetic tests for lysosomal acid lipase, signal transducing adaptor protein 1, ApoE, ABCG5 and ABCG8 in addition to routine LDLR, ApoB, PCSK9 and LDLRAP1 genetic tests, which can help in diagnosis and differential diagnosis (Cao et al., 2018; Cao et al., 2021). Here, LDLRAP1 is linked to familial hyperaldosteronism.