To verify thein vitro results, xenograft tumor models were established by subcutaneous injection of Hey cells transduced with empty vector or a lentiviral plasmid containing a shRNA targeting KCNMB2-AS1 (sh-KCNMB2-AS1 sense: 5′-CCGGGCTAGCTTCTCGTGTGCTTGTCTCGAGACAAGCACACGAGAAGCTAGCTTTTTG-3′, and antisense: 5′-AATTCAAAAAGCTAGCTTCTCGTGTGCTTGTCTCGAGACAAGCACACGAGAAGCTAGC-3′). Here, KCNMB2 is linked to neoplasm.