According to IF staining in Figures 1F and 7H, MGFs (CD90+) from the periodontitis group, were observed with higher expression of IL‐α/β, in which group, more severe bone resorption, periodontal ligament destruction and inflammatory cell infiltration occurred, suggesting that the inflammasome activation in GFs is partially involved in periodontal inflammation. The gene discussed is TNFRSF9; the disease is periodontitis.